Scientific Literature on Nanotechnology

Bispecific antibodies targeting tumor-associated antigens and neutralizing complement regulators increase the efficacy of antibody-based immunotherapy in mice

In this paper is shown the development a novel strategy to enhance complement-dependent cytotoxicity using bispecific antibodies (bsAbs) that neutralize the C-regulators CD55 and CD59 to enhance C-mediated functions.

Implementation of a Microwave-assisted Tissue-processing System and an Automated Embedding System for Breast Needle Core Biopsy Samples Morphology, Immunohistochemistry, and FISH Evaluation

The aim of this study was to evaluate whether breast needle core biopsy processed with the microwave-assisted tissue-processing system and automatically embedded show good-quality histology preparations and whether they are suitable for the assessment of estrogen receptor (ER), progesterone receptor (PR), Ki-67, and HER2 in breast carcinoma.

Trehalose preserves the integrity of lyophilized phycoerythrin-antihuman CD8 antibody conjugates and enhances their thermal stability in flow cytometric assays

In this work, is tested the ability of trehalose in protecting R-Phycoerythrin (R-PE), a pigment-protein complex widely used as fluorescent marker, from thermal denaturation. Once embedded into a dried trehalose matrix, R-PE retains its optical absorption-emission characteristics even when exposed to 70°C for h or when subjected to freeze-drying