The silica matrix which is part of the nanoparticles not only offers protection to the molecules it contains, but also allows conjugation of more fluorophore molecules per biomolecule unit, thus resulting in a stronger and more stable signal.

In cytometry, these features avoid problems due to environmentally caused changes in the sensitive fluorophores that compose tandem dyes, thus resulting in a more stable signal that does not require continuous compensation.

In microscopy applications, instead, the increased stability allows the operator to focus and capture images calmly.

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